MDM2 - MDM2 proto-oncogene Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 403693

About MDM2

Primary_assembly 10: 11,016,172-11,087,383 forward strand.ROS_Cfam_1.0:CM025109.1

This gene has 10 transcripts (splice variants), 254 orthologues and 1 paralogue.

MDM2 Products (1)

mRNA Protein Name
NM_001003103.2 NP_001003103.1 E3 ubiquitin-protein ligase Mdm2

MDM2 Protein Structure

MDM2

MDM2: cd17672 (24 - 106)

zf-RanBP

zf-RanBP: pfam00641 (298 - 327)

mRING-HC-C2H2C4_MDM2

mRING-HC-C2H2C4_MDM2: cd16783 (430 - 486)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 487 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Mdm2

  • MDM2 alpha

  • Mdm2 p53 binding protein homolog

  • Mdm2, p53 E3 ubiquitin protein ligase homolog

  • RING-type E3 ubiquitin transferase Mdm2

  • cdm2

  • double minute 2 homolog

  • double minute 2 protein

  • p53-binding protein Mdm2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-N0004 Oridonin 99.89% Phase 4

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130684 MDM2 ligand 5 98.02% Unkown
HY-128837 Nutlin carboxylic acid 98.63% Unkown
HY-P5930 HOXB7 8–25 / Unkown
HY-128837A (rel)-Nutlin carboxylic acid / Unkown
HY-128836 (4R,5S)-Nutlin carboxylic acid / Unkown
HY-168280 AS1411-C4-VH032 Degrader / Unkown
HY-148106 MEL23 Inhibitor / Unkown
HY-181813 PROTAC DHFR Degrader-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MDM2 NCBI NCBI:4193