XIAP - X-linked inhibitor of apoptosis Gene

Also Known as BIRC4

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 442989

About XIAP

Primary_assembly X: 97,072,142-97,127,986 forward strand.ROS_Cfam_1.0:CM025138.1

This gene has 1 transcript (splice variant), 217 orthologues and 4 paralogues.

XIAP Products (1)

mRNA Protein Name
NM_001284458.1 NP_001271387.1 E3 ubiquitin-protein ligase XIAP

XIAP Protein Structure

BIR

BIR: cd00022 (27 - 94)

BIR

BIR: smart00238 (161 - 231)

BIR

BIR: smart00238 (264 - 330)

UBA_BIRC4_8

UBA_BIRC4_8: cd14395 (365 - 414)

RING-HC_BIRC4_8

RING-HC_BIRC4_8: cd16714 (429 - 492)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 493 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase XIAP

  • X-linked inhibitor of apoptosis protein

  • baculoviral IAP repeat-containing 4

  • baculoviral IAP-repeat containing protein 4

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-15454 Xevinapant Antagonist 99.91% Phase 3
HY-13208 Xevinapant hydrochloride Antagonist 98.11% Phase 3
HY-168739 Topoisomerase I inhibitor 17 Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (27)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12600 AZD5582 Antagonist 99.61% Unkown
HY-17473 Embelin Antagonist 99.01% Unkown
HY-N0732 Jolkinolide B Inhibitor 99.65% Unkown
HY-110346 AZD5582 dihydrochloride Antagonist 99.92% Unkown
HY-151966 TD1092 Degrader 98.23% Unkown
HY-178226 PBX-7016 Inhibitor / Unkown
HY-125378 SBP-0636457 Antagonist 98.42% Unkown
HY-175352 Nurr1 agonist 14 Inducer 99.42% Unkown
HY-179633 ZLMT-72 Inhibitor / Unkown
HY-N18315 (2''S)-2'',3''-Dihydrodelicaflavone Modulator / Unkown
HY-111886 KHS108-MV1 Antagonist / Unkown
HY-168893 K882 Inhibitor / Unkown
HY-102051 XIAP/cIAP1 antagonist-1 Inhibitor / Unkown
HY-118522 TP-110 Inhibitor / Unkown
HY-175444 XIAP ligand-Linker Conjugate 1 Antagonist / Unkown
HY-175449 XIAP ligand 5 Antagonist / Unkown
HY-181533 IAP ligand 9 Ligand / Unkown
HY-12440 HM90822 Antagonist / Unkown
HY-123925 CSLP43 Inhibitor / Unkown
HY-179023 CDK9-IN-45 Inhibitor / Unkown
HY-175348 XB2M54 Antagonist / Unkown
HY-175450 XIAP ligand-Linker Conjugate 2 Antagonist / Unkown
HY-100682 T-3256336 Inhibitor / Unkown
HY-175448 GNE-1567 Antagonist / Unkown
HY-181532 IAP ligand 8 Ligand / Unkown
HY-181018 Topo I/DDX5-IN-1 Inhibitor / Unkown
HY-175925 XIAP ligand 6 Ligand / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens XIAP NCBI NCBI:331