PIKFYVE - phosphoinositide kinase, FYVE-type zinc finger containing Gene

Also Known as PIP5K3

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 478890

About PIKFYVE

Primary_assembly 37: 16,472,913-16,554,451 forward strand.ROS_Cfam_1.0:CM025136.1

This gene has 3 transcripts (splice variants), 205 orthologues and 20 paralogues.

PIKFYVE Products (5)

mRNA Protein Name
XM_038447796.1 XP_038303724.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1
XM_038447800.1 XP_038303728.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X4
XM_038447798.1 XP_038303726.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X2
XM_038447799.1 XP_038303727.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X3
XM_038447797.1 XP_038303725.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1

PIKFYVE Protein Structure

FYVE_PIKfyve_Fab1

FYVE_PIKfyve_Fab1: cd15725 (166 - 227)

DEP_PIKfyve

DEP_PIKfyve: cd04448 (369 - 450)

Fab1_TCP

Fab1_TCP: cd03334 (629 - 889)

PIPKc_PIKfyve

PIPKc_PIKfyve: cd17300 (1831 - 2097)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2112 a.a.
Protein Preferred Names Protein Names

1-phosphatidylinositol 3-phosphate 5-kinase

  • phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-14644 Apilimod Inhibitor 99.80% Phase 2
HY-14644A Apilimod mesylate Inhibitor 99.58% Phase 2

Pre-clinical Phase

Bioactive Molecules (18)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-118630 Vacuolin-1 Inhibitor 98.54% Unkown
HY-13228 YM-201636 Inhibitor 98.07% Unkown
HY-15982 APY0201 Inhibitor 99.42% Unkown
HY-119624 MOMIPP Inhibitor 99.00% Unkown
HY-155994 PIK5-12d Degrader 99.15% Unkown
HY-151473 PIKfyve-IN-1 Inhibitor 99.64% Unkown
HY-160477 DC-SX029 Inhibitor 98.07% Unkown
HY-153119 TMX-4153 Degrader 98.96% Unkown
HY-161619 RMC-113 Inhibitor 99.54% Unkown
HY-159625 WX8 Inhibitor 99.43% Unkown
HY-154956 PIKfyve-IN-2 Inhibitor 98.0% Unkown
HY-163943 UNI418 Inhibitor 99.61% Unkown
HY-163133 PIKfyve-IN-3 99.55% Unkown
HY-170909 PIKfyve-IN-4 Inhibitor 99.53% Unkown
HY-123876 AS2677131 Inhibitor / Unkown
HY-177432 TMX-4140 Inhibitor / Unkown
HY-177091 AS2795440 Inhibitor / Unkown
HY-175631 PIKfyve ligand-1 Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PIKFYVE NCBI NCBI:200576