ABR - ABR activator of RhoGEF and GTPase Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 480638 | Gene type: protein coding

About ABR

mRNA	Protein	Name
XM_038677640.1	XP_038533568.1	active breakpoint cluster region-related protein isoform X6
XM_038677637.1	XP_038533565.1	active breakpoint cluster region-related protein isoform X3
XM_038677635.1	XP_038533563.1	active breakpoint cluster region-related protein isoform X1
XM_038677636.1	XP_038533564.1	active breakpoint cluster region-related protein isoform X2
XM_038677638.1	XP_038533566.1	active breakpoint cluster region-related protein isoform X4
XM_038677639.1	XP_038533567.1	active breakpoint cluster region-related protein isoform X5

Protein Preferred Names

Protein Names

active breakpoint cluster region-related protein

LOW QUALITY PROTEIN: active breakpoint cluster region-related protein

ABR, RhoGEF and GTPase activating protein

active BCR-related

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13010	Laquinimod		99.46%	Yes

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-10528	Tasquinimod	Modulator	99.70%	Phase 3
HY-13743	Roquinimex	Inhibitor	99.69%	Phase 3
HY-W062904	Laquinimod sodium	Inhibitor	/	Phase 3
HY-100442	Paquinimod	Inhibitor	99.90%	Phase 2

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-141537	ABR-238901	Inhibitor	98.92%	Unkown
HY-100442S1	Paquinimod-d5-1	Inhibitor	98.19%	Unkown
HY-10528S	Tasquinimod-d3	Modulator	99.34%	Unkown
HY-13010S	Laquinimod-d5	Inhibitor	98.25%	Unkown
HY-RS00110	ABR Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-100442S	Paquinimod-d5	Inhibitor	/	Unkown
HY-RS17572	Abr Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24032	Abr Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99436	Anatumomab mafenatox	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	ABR	NCBI	NCBI:29
Macaca fascicularis	ABR	NCBI	NCBI:102126046
Mus musculus	ABR	NCBI	NCBI:109934
Rattus norvegicus	ABR	NCBI	NCBI:287537

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