PFDN2 - prefoldin subunit 2 Gene

Homo sapiens

Also known as PFD2

Gene ID: 5202 | Gene type: protein coding

About PFDN2

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,100,561-161,118,037 (from NCBI)

This gene has 2 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in fat (RPKM 33.7), brain (RPKM 30.3) and 25 other tissues.

Summary

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]

PFDN2 Products(1)

mRNA	Protein	Name
NM_012394.4	NP_036526.2	prefoldin subunit 2

PFDN2 Protein Structure

Prefoldin_2

0
100
154 a.a.

Protein Preferred Names

Protein Names

prefoldin subunit 2

prefoldin 2

Recombinant PFDN2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71197	PFDN2 Protein, Human (His)	Q9UHV9 (M1-S154)	≥95%

Related Diseases

Diseases

Alias

Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly

Asphyxiating Thoracic Dystrophy 4	SRTD4
Atd4	Jatd
Jeune Asphyxiating Thoracic Dystrophy	Jeune Syndrome 4

Variegate Porphyria

Porphyria Variegata	Protoporphyrinogen Oxidase Deficiency
VP	Ppox Deficiency
Porphyria, South African Type	Porphyria Variegata, Susceptibility To
Protocoproporphyria	Porphyria Variegate
Porphyria South African Type	Pv
Porphyria, Variegate	Vp - [Variegate Porphyria]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10358	PFDN2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PFDN2	RGD	RGD:1591406
Mus musculus	PFDN2	MGD	MGI:1276111
Bos taurus	PFDN2	VGNC	VGNC:59188
Macaca mulatta	PFDN2	VGNC	VGNC:106469
Felis catus	PFDN2	VGNC	VGNC:68802
Canis familiaris	PFDN2	VGNC	VGNC:44440
Others	PFDN2	NCBI

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