2. Gene
  3. MPL - MPL proto-oncogene, thrombopoietin receptor Gene

MPL - MPL proto-oncogene, thrombopoietin receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus
Gene ID: 528492 | Gene type: protein coding

About MPL

Primary_assembly 3: 102,663,876-102,678,104 reverse strand.ARS-UCD1.2:CM008170.2

This gene has 2 transcripts (splice variants), 186 orthologues and 7 paralogues.

MPL Products(1)

mRNA Protein Name
NM_001192663.1 NP_001179592.1 thrombopoietin receptor precursor

MPL Protein Structure

FN3

FN3: cl21522 (24 - 127)

FN3

FN3: cd00063 (392 - 482)

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  • 644 a.a.
Protein Preferred Names Protein Names

thrombopoietin receptor

myeloproliferative leukemia virus oncogene

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-122620 Rafutrombopag (tautomerism) 98.33% Phase 4
HY-145589 Rafutrombopag 95.29% Phase 4
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990685 Romiplostim Agonist ≥99.0% Phase 4
Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148748 Butyzamide Activator 99.83% Unkown
HY-112486 TA-316 99.50% Unkown
HY-112486G TA-316 (GMP) Agonist / Unkown
HY-148748G Butyzamide (GMP) Activator / Unkown
HY-144002 RIBI-529 / Unkown
HY-RS08616 MPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-159671A 3D-Monophosphoryl Lipid (14) triethylamine Agonist / Unkown
HY-159671B 3D-Monophosphoryl Lipid (14) ammonium Agonist / Unkown
HY-159672 3D-Monophosphoryl Lipid (12,16) Agonist / Unkown
HY-159672A 3D-Monophosphoryl Lipid (12,16) free acid Agonist / Unkown
HY-159672B 3D-Monophosphoryl Lipid (12,16) triethylamine Agonist / Unkown
HY-182369 VA06 Inhibitor / Unkown
HY-NP074 Maclura Pomifera Lectin / Unkown
HY-RS08617 Mpl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08618 Mpl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-159671 3D-Monophosphoryl Lipid (14) Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MPL NCBI NCBI:4352
Canis familiaris MPL NCBI NCBI:610801
Macaca fascicularis MPL NCBI NCBI:101864977
Canis lupus familiaris MPL NCBI
Mus musculus MPL NCBI NCBI:17480
Susscrofa domestica MPL NCBI
Leporidae MPL NCBI
Rattus norvegicus MPL NCBI NCBI:366455
Macaca mulatta MPL NCBI NCBI:723813