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Cat. No.: HY-148748G

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Butyzamide (GMP)

Name: Butyzamide (GMP)
Brand: MedChemExpress
SKU: HY-148748G
Price: 1460.00 USD
Availability: InStock
Rating: 5 (1 reviews)

고객리뷰

Based on 1 Customer Validation

Butyzamide (GMP) is Butyzamide (HY-148748) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of platelets in mouse xenotransplantation assay.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1110767-45-7
화학식: C₂₉H₃₂Cl₂N₂O₅S
분자량:591.55

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Butyzamide (GMP) Chemical Structure

CAS No.: 1110767-45-7

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

All JAK Isoforms :

All STAT Isoforms :

All p38 MAPK Isoforms :

In Vitro

Butyzamide (GMP) (3 μM; 15 min) induces the phosphorylation of JAK2, STAT3, STAT5 and MAPK in Ba/F3-hMpl cells^[1].
Butyzamide (GMP) (3 μM; 48 h) induces colony-forming unit-megakaryocyte and polyploid meggakaryocytes from human CD34⁺ hematopoietic progenitor cellls^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Butyzamide (GMP) (10 mg/kg, 50 mg/kg; p.o.; once daily for 20 days) increases platelets in NOG mice transplanted with human fetal liver-derived CD34⁺ cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1110767-45-7
Appearance Solid
분자량 591.55
화학식 C₂₉H₃₂Cl₂N₂O₅S
Color White to off-white
SMILES

CCCOC(C(C)(C)C)C1=CC=CC(C2=CSC(NC(C3=CC(Cl)=C(/C=C(C(O)=O)\C)C(Cl)=C3)=O)=N2)=C1OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nogami W, et al. The effect of a novel, small non-peptidyl molecule butyzamide on human thrombopoietin receptor and megakaryopoiesis. Haematologica. 2008 Oct;93(10):1495-504. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References

상품명:
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Butyzamide (GMP)

Eltrombopag

Butyzamide

Eltrombopag Olamine

Eltrombopag (Standard)

Eltrombopag Olamine (Standard)

All JAK Isoforms

All STAT Isoforms

All p38 MAPK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

Butyzamide (GMP)

Eltrombopag

Butyzamide

Eltrombopag Olamine

Eltrombopag (Standard)

Eltrombopag Olamine (Standard)

All JAK Isoforms

All STAT Isoforms

All p38 MAPK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Butyzamide (GMP) Related Classifications

HY-148748G Related Classifications

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