Orc6 - origin recognition complex, subunit 6 Gene

Also Known as Orc6l; 6720420I10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56452

Summary

Predicted to enable DNA binding activity. Acts upstream of or within DNA-dependent DNA replication. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of nuclear origin of replication recognition complex. Is expressed in several structures, including brain ventricular layer; early conceptus; jaw; liver lobe; and submandibular gland primordium. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Orthologous to human ORC6 (origin recognition complex subunit 6). [provided by Alliance of Genome Resources, Apr 2022]

Orc6 Products (2)

mRNA Protein Name
NM_001163791.1 NP_001157263.1 origin recognition complex subunit 6 isoform b
NM_019716.2 NP_062690.2 origin recognition complex subunit 6 isoform a

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA-templated DNA replication IMP
IMP: Inferred from mutant phenotype
20219456 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

origin recognition complex subunit 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09830 ORC6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Orc6 NCBI NCBI:23594