GRAMD1A - GRAM domain containing 1A Gene

Homo sapiens

Also known as KIAA1533

Gene ID: 57655 | Gene type: protein coding

About GRAMD1A

This gene has 15 transcripts (splice variants), 191 orthologues and 4 paralogues. Ubiquitous expression in lung (RPKM 13.7), spleen (RPKM 13.3) and 25 other tissues.

Summary

Predicted to enable Cholesterol binding activity and Cholesterol transfer activity. Predicted to be involved in cellular response to Cholesterol. Located in cytosol; organelle membrane contact site; and plasma membrane. Is extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

GRAMD1A Products(5)

mRNA	Protein	Name
NM_001136199.3	NP_001129671.1	protein Aster-A isoform 2
NM_001320034.2	NP_001306963.1	protein Aster-A isoform 3
NM_001320035.2	NP_001306964.1	protein Aster-A isoform 4
NM_001320036.2	NP_001306965.1	protein Aster-A isoform 5
NM_020895.5	NP_065946.2	protein Aster-A isoform 1

GRAMD1A Protein Structure

GRAM

0
200
400
600
724 a.a.

Protein Preferred Names

Protein Names

protein Aster-A

GRAM domain-containing protein 1A

Related Diseases

Diseases

Alias

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05772	GRAMD1A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GRAMD1A	VGNC	VGNC:73029
Canis familiaris	GRAMD1A	VGNC	VGNC:41465
Bos taurus	GRAMD1A	VGNC	VGNC:29622
Mus musculus	GRAMD1A	MGD	MGI:105490
Rattus norvegicus	GRAMD1A	RGD	RGD:1311022
Felis catus	GRAMD1A	VGNC	VGNC:62701

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