NCKAP5L - NCK associated protein 5 like Gene

Also Known as Cep169; FP1193; KIAA1602

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57701

About NCKAP5L

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:49,791,152-49,828,413 (from NCBI)

This gene has 5 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in placenta (RPKM 5.5), testis (RPKM 5.4) and 25 other tissues.

Summary

Involved in microtubule bundle formation and microtubule depolymerization. Located in centrosome and microtubule plus-end. [provided by Alliance of Genome Resources, Apr 2022]

NCKAP5L Products (2)

mRNA Protein Name
NM_001037806.4 NP_001032895.2 nck-associated protein 5-like
NM_001368048.1 NP_001354977.1 nck-associated protein 5-like

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26485573 GOA
Biological Process GO Annotation Evidence References Source
involved in microtubule bundle formation IDA
IDA: Inferred from direct assay
26485573 GOA
involved in microtubule depolymerization IMP
IMP: Inferred from mutant phenotype
26485573 GOA
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
26485573 GOA
located in microtubule plus-end IDA
IDA: Inferred from direct assay
26485573 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NCKAP5L Protein Structure

NCKAP5

NCKAP5: Nck-associated protein 5, Peripheral clock protein (879 - 1183)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1334 a.a.
Protein Preferred Names Protein Names

nck-associated protein 5-like

  • NCKAP5-like

Related Diseases

Diseases Alias
Spherocytosis, Type 2

  • Hereditary Spherocytosis Type 2

  • SPH2

  • Spherocytosis, Hereditary, 2

  • Hs2

  • Hereditary Spherocytosis 2

  • Spherocytosis 2

  • Spherocytosis, Type 2, Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09085 NCKAP5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NCKAP5L VGNC VGNC:43655
Felis catus NCKAP5L VGNC VGNC:63739
Macaca mulatta NCKAP5L VGNC VGNC:75038
Rattus norvegicus NCKAP5L RGD RGD:1561571
Bos taurus NCKAP5L VGNC VGNC:31917
Mus musculus NCKAP5L MGD MGI:3609653
Others NCKAP5L NCBI