MPL - MPL proto-oncogene, thrombopoietin receptor Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 610801

About MPL

Primary_assembly 15: 16,978,816-16,993,003 reverse strand.ROS_Cfam_1.0:CM025114.1

This gene has 1 transcript (splice variant), 186 orthologues and 7 paralogues.

MPL Products (2)

mRNA Protein Name
XM_038687983.1 XP_038543911.1 thrombopoietin receptor isoform X1
XM_038687984.1 XP_038543912.1 thrombopoietin receptor isoform X2

MPL Protein Structure

EpoR_lig-bind

EpoR_lig-bind: pfam09067 (24 - 127)

FN3

FN3: cd00063 (392 - 482)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 628 a.a.
Protein Preferred Names Protein Names

thrombopoietin receptor

  • myeloproliferative leukemia virus oncogene

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-122620 Rafutrombopag (tautomerism) 98.33% Phase 4
HY-145589 Rafutrombopag 95.29% Phase 4

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148748 Butyzamide Activator 99.83% Unkown
HY-112486 TA-316 99.50% Unkown
HY-112486G TA-316 (GMP) Agonist / Unkown
HY-148748G Butyzamide (GMP) Activator / Unkown
HY-144002 RIBI-529 / Unkown
HY-RS08616 MPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-159671A 3D-Monophosphoryl Lipid (14) triethylamine Agonist / Unkown
HY-159671B 3D-Monophosphoryl Lipid (14) ammonium Agonist / Unkown
HY-159672 3D-Monophosphoryl Lipid (12,16) Agonist / Unkown
HY-159672A 3D-Monophosphoryl Lipid (12,16) free acid Agonist / Unkown
HY-159672B 3D-Monophosphoryl Lipid (12,16) triethylamine Agonist / Unkown
HY-182369 VA06 Inhibitor / Unkown
HY-NP074 Maclura Pomifera Lectin / Unkown
HY-RS08617 Mpl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08618 Mpl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-159671 3D-Monophosphoryl Lipid (14) Agonist / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990685 Romiplostim Agonist ≥99.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MPL NCBI NCBI:4352