DMRTA2 - DMRT like family A2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 63950

About DMRTA2

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:50,417,550-50,423,443 (from NCBI)

This gene has 2 transcripts (splice variants), 185 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within nervous system development and skeletal muscle cell differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DMRTA2 Products (1)

mRNA Protein Name
NM_032110.3 NP_115486.1 doublesex- and mab-3-related transcription factor A2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DMRTA2 Protein Structure

DM

DM: DM DNA binding domain (66 - 112)

DMA

DMA: DMRTA motif (313 - 351)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 542 a.a.
Protein Preferred Names Protein Names

doublesex- and mab-3-related transcription factor A2

  • doublesex- and mab-3-related transcription factor 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03832 DMRTA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DMRTA2 MGD MGI:2653629
Macaca mulatta DMRTA2 VGNC VGNC:106349
Felis catus DMRTA2 VGNC VGNC:107523
Bos taurus DMRTA2 VGNC VGNC:28114
Rattus norvegicus DMRTA2 RGD RGD:1308173
Others DMRTA2 NCBI