Agpat2 - 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) Gene

Also Known as BSCL; BSCL1; LPAAB; 1-AGPAT 2; LPAAT-beta; 2510002J07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67512

Summary

Enables 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process and positive regulation of cytokine production. Predicted to act upstream of or within lipid metabolic process. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and urinary system. Used to study congenital generalized lipodystrophy type 1. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to human AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Agpat2 Products (1)

mRNA Protein Name
NM_026212.2 NP_080488.1 1-acyl-sn-glycerol-3-phosphate acyltransferase beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-acylglycerol-3-phosphate O-acyltransferase activity IDA
IDA: Inferred from direct assay
15367102 MGI
enables 1-acylglycerol-3-phosphate O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
19187773 MGI
Biological Process GO Annotation Evidence References Source
involved in triglyceride biosynthetic process IGI
IGI: Inferred from genetic interaction
19187773 MGI
involved in triglyceride biosynthetic process IMP
IMP: Inferred from mutant phenotype
16495223 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
16449762 MGI
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
16449762 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-acyl-sn-glycerol-3-phosphate acyltransferase beta

  • 1-AGP acyltransferase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00457 AGPAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21818 Agpat2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28334 Agpat2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agpat2 NCBI NCBI:10555