Dcxr - dicarbonyl L-xylulose reductase Gene

Also Known as XR; 0610038K04Rik; 1810027P18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67880

Summary

Enables L-xylulose reductase (NADP+) activity. Involved in glucose metabolic process. Acts upstream of or within NADP metabolic process and xylulose metabolic process. Located in brush border and microvillus. Is expressed in adrenal gland; alimentary system; genitourinary system; respiratory system; and thymus. Human ortholog(s) of this gene implicated in pentosuria. Orthologous to human DCXR (dicarbonyl and L-xylulose reductase). [provided by Alliance of Genome Resources, Apr 2022]

Dcxr Products (2)

mRNA Protein Name
NM_001347608.1 NP_001334537.1 L-xylulose reductase isoform 2
NM_026428.3 NP_080704.2 L-xylulose reductase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-xylulose reductase (NADPH) activity IDA
IDA: Inferred from direct assay
11882650 MGI
enables oxidoreductase activity, acting on CH-OH group of donors IDA
IDA: Inferred from direct assay
11882650 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11882650 MGI
Biological Process GO Annotation Evidence References Source
involved in D-glucuronate catabolic process to D-xylulose 5-phosphate IDA
IDA: Inferred from direct assay
11882650 MGI
acts upstream of or within NADP metabolic process IDA
IDA: Inferred from direct assay
11882650 MGI
involved in glucose metabolic process IDA
IDA: Inferred from direct assay
11882650 MGI
acts upstream of or within xylulose metabolic process IDA
IDA: Inferred from direct assay
11882650 MGI
Cellular Component GO Annotation Evidence References Source
located in brush border IDA
IDA: Inferred from direct assay
11882650 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
38160 MGI
located in microvillus IDA
IDA: Inferred from direct assay
11882650 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

L-xylulose reductase

  • diacetyl/L-xylulose reductase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03602 DCXR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18348 Dcxr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24827 Dcxr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dcxr NCBI NCBI:51181