Erfe - erythroferrone Gene

Also Known as Fam132b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 681056

Summary

Predicted to enable hormone activity and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of gluconeogenesis; positive regulation of glucose import; and positive regulation of Insulin Receptor signaling pathway. Predicted to act upstream of or within positive regulation of fatty acid transport and regulation of fatty acid metabolic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human ERFE (erythroferrone). [provided by Alliance of Genome Resources, Apr 2022]

Erfe Products (1)

mRNA Protein Name
NM_001377080.1 NP_001364009.1 erythroferrone precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
30566056 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
30566056 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

erythroferrone

  • complement C1q tumor necrosis factor-related protein 15

  • family with sequence similarity 132, member B

  • myonectin

  • protein FAM132B

  • rCG55642-like

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99590A Sotatercept (mIgG2a) Inhibitor 99.93% Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04489 ERFE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16922 Erfe Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23365 Erfe Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Erfe NCBI NCBI:151176