Pmvk - phosphomevalonate kinase Gene

Also Known as PMK; PMKA; PMKASE; 1110011E12Rik; 2900002L22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68603

Summary

Enables phosphomevalonate kinase activity. Predicted to be involved in Cholesterol biosynthetic process and isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to act upstream of or within Cholesterol metabolic process; phosphorylation; and steroid biosynthetic process. Predicted to be located in cytosol. Is expressed in early conceptus. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human PMVK (phosphomevalonate kinase). [provided by Alliance of Genome Resources, Apr 2022]

Pmvk Products (3)

mRNA Protein Name
NM_001310640.1 NP_001297569.1 phosphomevalonate kinase isoform 3
NM_026784.3 NP_081060.2 phosphomevalonate kinase isoform 1
NM_027348.1 NP_081624.1 phosphomevalonate kinase isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables phosphomevalonate kinase activity IDA
IDA: Inferred from direct assay
11792727 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphomevalonate kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10774 PMVK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19153 Pmvk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25642 Pmvk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmvk NCBI NCBI:10654