PAK3 - p21 (RAC1) activated kinase 3 Gene
Species: Macaca mulatta
Gene Type: protein coding
Gene ID: 706217
About PAK3
Primary_assembly X: 107,644,902-107,931,353 forward strand.Mmul_10:CM014356.1
This gene has 9 transcripts (splice variants), 213 orthologues and 35 paralogues.
PAK3 Products (17)
| mRNA | Protein | Name |
|---|---|---|
| XM_015128015.2 | XP_014983501.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_028842157.1 | XP_028697990.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_015128022.2 | XP_014983508.1 | serine/threonine-protein kinase PAK 3 isoform X4 |
| XM_015128020.2 | XP_014983506.1 | serine/threonine-protein kinase PAK 3 isoform X3 |
| XM_028842163.1 | XP_028697996.1 | serine/threonine-protein kinase PAK 3 isoform X4 |
| XM_015128019.2 | XP_014983505.1 | serine/threonine-protein kinase PAK 3 isoform X2 |
| XM_028842161.1 | XP_028697994.1 | serine/threonine-protein kinase PAK 3 isoform X3 |
| XM_028842156.1 | XP_028697989.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_028842158.1 | XP_028697991.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_015128018.2 | XP_014983504.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_015128021.2 | XP_014983507.1 | serine/threonine-protein kinase PAK 3 isoform X4 |
| XM_015128013.2 | XP_014983499.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_028842159.1 | XP_028697992.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_028842160.1 | XP_028697993.1 | serine/threonine-protein kinase PAK 3 isoform X2 |
| XM_015128012.2 | XP_014983498.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_015128016.2 | XP_014983502.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_028842162.1 | XP_028697995.1 | serine/threonine-protein kinase PAK 3 isoform X3 |
PAK3 Protein Structure
PBD
PBD: pfam00786 (68 - 140)
STKc_PAK_I
STKc_PAK_I: cd06647 (274 - 529)
- 0
- 100
- 200
- 300
- 400
- 500
- 562 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine/threonine-protein kinase PAK 3 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-13007 | PF-3758309 | Inhibitor | 99.79% | Phase 1 |
| HY-13007B | PF-3758309 dihydrochloride | Inhibitor | / | Phase 1 |
| HY-13007A | PF-3758309 hydrochloride | Inhibitor | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-15542A | FRAX597 | Inhibitor | 99.36% | Unkown |
| HY-15542B | FRAX486 | Inhibitor | 98.10% | Unkown |
| HY-123739 | LDN-0028574 | Inhibitor | / | Unkown |
| HY-146786 | ZMF-10 | Inhibitor | / | Unkown |
| HY-178812 | PI3Kα-IN-27 | Inhibitor | / | Unkown |
| HY-118606 | LDN-0044878 | Inhibitor | / | Unkown |
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