2. Gene
  3. PIKFYVE - phosphoinositide kinase, FYVE-type zinc finger containing Gene

PIKFYVE - phosphoinositide kinase, FYVE-type zinc finger containing Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 710115 | Gene type: protein coding

About PIKFYVE

Primary_assembly 12: 95,684,864-95,772,744 forward strand.Mmul_10:CM014347.1

This gene has 10 transcripts (splice variants), 205 orthologues and 14 paralogues.

PIKFYVE Products(21)

mRNA Protein Name
XM_015110830.2 XP_014966316.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X10
XM_015110821.2 XP_014966307.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1
XM_015110823.2 XP_014966309.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X2
XM_015110824.2 XP_014966310.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X3
XM_015110822.2 XP_014966308.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1
XM_015110837.2 XP_014966323.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X16
XM_001108540.4 XP_001108540.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X4
XM_015110838.1 XP_014966324.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X16
XM_015110827.2 XP_014966313.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X8
XM_028831053.1 XP_028686886.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X5
XM_015110831.2 XP_014966317.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X11
XM_015110836.2 XP_014966322.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X15
XM_015110833.2 XP_014966319.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X12
XM_015110825.2 XP_014966311.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X4
XM_028831055.1 XP_028686888.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X14
XM_015110835.2 XP_014966321.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X13
XM_015110832.2 XP_014966318.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X11
XM_015110826.2 XP_014966312.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X7
XM_028831054.1 XP_028686887.1 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6
XM_015110834.2 XP_014966320.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X12
XM_015110829.2 XP_014966315.2 1-phosphatidylinositol 3-phosphate 5-kinase isoform X9

PIKFYVE Protein Structure

FYVE_PIKfyve_Fab1

FYVE_PIKfyve_Fab1: cd15725 (165 - 226)

DEP_PIKfyve

DEP_PIKfyve: cd04448 (368 - 449)

Fab1_TCP

Fab1_TCP: cd03334 (628 - 888)

PIPKc_PIKfyve

PIPKc_PIKfyve: cd17300 (1829 - 2095)

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  • 1600
  • 2000
  • 2110 a.a.
Protein Preferred Names Protein Names

1-phosphatidylinositol 3-phosphate 5-kinase

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-14644 Apilimod Inhibitor 99.80% Phase 2
HY-14644A Apilimod mesylate Inhibitor 99.58% Phase 2
Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-118630 Vacuolin-1 Inhibitor 98.54% Unkown
HY-13228 YM-201636 Inhibitor 98.05% Unkown
HY-15982 APY0201 Inhibitor 99.42% Unkown
HY-119624 MOMIPP Inhibitor 99.00% Unkown
HY-155994 PIK5-12d Degrader 99.15% Unkown
HY-151473 PIKfyve-IN-1 Inhibitor 99.64% Unkown
HY-160477 DC-SX029 Inhibitor 98.07% Unkown
HY-153119 TMX-4153 Degrader 98.96% Unkown
HY-159625 WX8 Inhibitor 99.43% Unkown
HY-161619 RMC-113 Inhibitor 99.54% Unkown
HY-154956 PIKfyve-IN-2 Inhibitor 98.0% Unkown
HY-163133 PIKfyve-IN-3 99.55% Unkown
HY-163943 UNI418 Inhibitor 99.61% Unkown
HY-170909 PIKfyve-IN-4 Inhibitor 99.53% Unkown
HY-177432 TMX-4140 Inhibitor / Unkown
HY-177091 AS2795440 Inhibitor / Unkown
HY-123876 AS2677131 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PIKFYVE NCBI NCBI:200576