MDM2 - MDM2 proto-oncogene Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 718284

About MDM2

Primary_assembly 11: 68,342,378-68,377,008 forward strand.Mmul_10:CM014346.1

This gene has 3 transcripts (splice variants), 253 orthologues and 1 paralogue.

MDM2 Products (1)

mRNA Protein Name
NM_001266402.1 NP_001253331.1 E3 ubiquitin-protein ligase Mdm2

MDM2 Protein Structure

MDM2

MDM2: cd17672 (30 - 112)

zf-RanBP

zf-RanBP: pfam00641 (304 - 333)

mRING-HC-C2H2C4_MDM2

mRING-HC-C2H2C4_MDM2: cd16783 (440 - 496)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 497 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Mdm2

  • Mdm2 p53 binding protein homolog

  • Mdm2, p53 E3 ubiquitin protein ligase homolog

  • Mdm2, transformed 3T3 cell double minute 2, p53 binding protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-N0004 Oridonin 99.89% Phase 4

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130684 MDM2 ligand 5 98.02% Unkown
HY-128837 Nutlin carboxylic acid 98.63% Unkown
HY-P5930 HOXB7 8–25 / Unkown
HY-128837A (rel)-Nutlin carboxylic acid / Unkown
HY-128836 (4R,5S)-Nutlin carboxylic acid / Unkown
HY-168280 AS1411-C4-VH032 Degrader / Unkown
HY-148106 MEL23 Inhibitor / Unkown
HY-181813 PROTAC DHFR Degrader-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MDM2 NCBI NCBI:4193