Pcgf5 - polycomb group ring finger 5 Gene

Also Known as 0610009F02Rik; 1110054A01Rik; 5830406C17Rik; 5830443C21Rik; 9530023M17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76073

Summary

Predicted to enable metal ion binding activity. Involved in histone H2A-K119 monoubiquitination and inactivation of X chromosome by genetic imprinting. Part of PcG protein complex. Colocalizes with X chromosome. Is expressed in bladder; heart; and ureter. Orthologous to human PCGF5 (polycomb group ring finger 5). [provided by Alliance of Genome Resources, Apr 2022]

Pcgf5 Products (5)

mRNA Protein Name
NM_001368690.1 NP_001355619.1 polycomb group RING finger protein 5 isoform 1
NM_001368691.1 NP_001355620.1 polycomb group RING finger protein 5 isoform 1
NM_001368692.1 NP_001355621.1 polycomb group RING finger protein 5 isoform 2
NM_001368693.1 NP_001355622.1 polycomb group RING finger protein 5 isoform 2
NM_029508.4 NP_083784.1 polycomb group RING finger protein 5 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone H2AK119 ubiquitin ligase activity IMP
IMP: Inferred from mutant phenotype
28596365 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28596365 MGI
Biological Process GO Annotation Evidence References Source
involved in random inactivation of X chromosome IMP
IMP: Inferred from mutant phenotype
28596365 MGI
Cellular Component GO Annotation Evidence References Source
part of PcG protein complex IDA
IDA: Inferred from direct assay
28596365 MGI
colocalizes with X chromosome IDA
IDA: Inferred from direct assay
28596365 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polycomb group RING finger protein 5

  • RING finger protein 159

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10148 PCGF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcgf5 NCBI NCBI:84333