Cmya5 - cardiomyopathy associated 5 Gene

Also Known as Tims; Srfsd; sr553; 2310076E16Rik; 2310076E21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76469

Summary

Enables identical protein binding activity. Acts upstream of or within negative regulation of calcineurin-NFAT signaling cascade; negative regulation of phosphoprotein Phosphatase activity; and regulation of skeletal muscle adaptation. Located in costamere. Is expressed in heart; skeletal muscle; and somite. Orthologous to human CMYA5 (cardiomyopathy associated 5). [provided by Alliance of Genome Resources, Apr 2022]

Cmya5 Products (1)

mRNA Protein Name
NM_023821.3 NP_076310.2 cardiomyopathy-associated protein 5
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
14688250 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14688250 MGI
enables protein phosphatase inhibitor activity IDA
IDA: Inferred from direct assay
21427212 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of calcineurin-NFAT signaling cascade IGI
IGI: Inferred from genetic interaction
21427212 MGI
acts upstream of or within regulation of skeletal muscle adaptation IGI
IGI: Inferred from genetic interaction
21427212 MGI
Cellular Component GO Annotation Evidence References Source
located in costamere IDA
IDA: Inferred from direct assay
16407236 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cardiomyopathy-associated protein 5

  • TRIM-like protein

  • heart and skeletal muscle-specific and sprouty domain-containing

  • myospryn

  • stretch response protein 553

  • stretch-responsive fibronectin protein type 3

Orthologs Information

Species Symbol Source ID
Homo sapiens Cmya5 NCBI NCBI:202333