Cyren - cell cycle regulator of NHEJ Gene

Also Known as Mri; 3110062M04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78412

Summary

Involved in double-strand break repair via nonhomologous end joining and immunoglobulin V(D)J recombination. Is active in site of double-strand break. Is expressed in several structures, including adipose tissue; alimentary system; eye; male reproductive gland or organ; and nervous system. Orthologous to human CYREN (cell cycle regulator of NHEJ). [provided by Alliance of Genome Resources, Apr 2022]

Cyren Products (3)

mRNA Protein Name
NM_001135611.1 NP_001129083.1 cell cycle regulator of non-homologous end joining isoform 1
NM_001347101.1 NP_001334030.1 cell cycle regulator of non-homologous end joining isoform 2
NM_199145.2 NP_954596.1 cell cycle regulator of non-homologous end joining isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables damaged DNA binding IDA
IDA: Inferred from direct assay
30017584 MGI
enables molecular adaptor activity EXP
EXP: Inferred from Experiment
30017584 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30017584 MGI
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IDA
IDA: Inferred from direct assay
30017584 MGI
involved in double-strand break repair via nonhomologous end joining IDA
IDA: Inferred from direct assay
30017584 MGI
involved in double-strand break repair via nonhomologous end joining IMP
IMP: Inferred from mutant phenotype
30017584 MGI
involved in immunoglobulin V(D)J recombination IMP
IMP: Inferred from mutant phenotype
30017584 MGI
involved in positive regulation of double-strand break repair via nonhomologous end joining IMP
IMP: Inferred from mutant phenotype
30017584 MGI
involved in protein homooligomerization EXP
EXP: Inferred from Experiment
30017584 MGI
involved in protein localization to site of double-strand break IDA
IDA: Inferred from direct assay
30017584 MGI
Cellular Component GO Annotation Evidence References Source
part of DNA repair complex IPI
IPI: Inferred from physical interaction
30017584 MGI
is active in site of double-strand break IDA
IDA: Inferred from direct assay
30017584 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell cycle regulator of non-homologous end joining

  • modulator of retrovirus infection homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03490 CYREN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22464 Cyren Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28987 Cyren Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyren NCBI NCBI:78996