GAL3ST4 - galactose-3-O-sulfotransferase 4 Gene

Also Known as GAL3ST-4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79690

About GAL3ST4

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,159,244-100,168,617 (from NCBI)

This gene has 8 transcripts (splice variants), 202 orthologues and 3 paralogues. Ubiquitous expression in skin (RPKM 11.3), salivary gland (RPKM 5.3) and 21 other tissues.

Summary

This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates. [provided by RefSeq, Jul 2008]

GAL3ST4 Products (1)

mRNA Protein Name
NM_024637.5 NP_078913.3 galactose-3-O-sulfotransferase 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables galactose 3-O-sulfotransferase activity IDA
IDA: Inferred from direct assay
11333265 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within glycoprotein biosynthetic process IDA
IDA: Inferred from direct assay
11333265 GOA
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
11333265 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GAL3ST4 Protein Structure

Gal-3-0_sulfotr

Gal-3-0_sulfotr: Galactose-3-O-sulfotransferase (18 - 227)

Gal-3-0_sulfotr

Gal-3-0_sulfotr: Galactose-3-O-sulfotransferase (286 - 469)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 486 a.a.
Protein Preferred Names Protein Names

galactose-3-O-sulfotransferase 4

  • beta-galactose-3-O-sulfotransferase 4

Related Diseases

Diseases Alias
Fanconi Anemia, Complementation Group G

  • Fanconi Anemia Complementation Group G

  • FANCG
Scoliosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05240 GAL3ST4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GAL3ST4 VGNC VGNC:54026
Mus musculus GAL3ST4 MGD MGI:1916254
Rattus norvegicus GAL3ST4 RGD RGD:1561105
Macaca mulatta GAL3ST4 VGNC VGNC:72770
Felis catus GAL3ST4 VGNC VGNC:62437
Bos taurus GAL3ST4 VGNC VGNC:29216
Others GAL3ST4 NCBI