2. Gene
  3. Lin28a - lin-28 homolog A Gene

Lin28a - lin-28 homolog A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lin28; Tex17; Lin-28; Gm10299; lin-28A

Gene ID: 83557 | Gene type: protein coding

About Lin28a

Summary

Enables RNA binding activity and translation initiation factor binding activity. Involved in several processes, including RNA metabolic process; positive regulation of intracellular signal transduction; and regulation of gene expression. Acts upstream of or within several processes, including miRNA metabolic process; negative regulation of glial cell differentiation; and regulation of gene expression. Located in nucleolus and rough endoplasmic reticulum. Is expressed in several structures, including early conceptus; embryo ectoderm; gonad; limb primordium; and tooth. Used to study nephroblastoma. Orthologous to human LIN28A (lin-28 homolog A). [provided by Alliance of Genome Resources, Apr 2022]

Lin28a Products(1)

mRNA Protein Name
NM_145833.1 NP_665832.1 protein lin-28 homolog A
Protein Preferred Names Protein Names

protein lin-28 homolog A

RNA-binding protein LIN-28

testis expressed gene 17

testis-expressed protein 17

Lin28a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Lin28a Q8K3Y3 Dis3l2 Mus musculus Q8CI75
Anti Tag CoIP
23594738
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-168437 LIN28-IN-2 99.51% Unkown
HY-112659 Lin28-let-7 antagonist 1 Antagonist 99.43% Unkown
HY-100692 Lin28-let-7a antagonist 1 Antagonist 99.48% Unkown
HY-168346 TS-002455 / Unkown
HY-177782 SB1349 Degrader / Unkown
HY-RS07671 LIN28A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174590 Human LIN28A mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lin28a NCBI NCBI:79727