Lin28-let-7 antagonist 1
Based on 1 Customer Validation
Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells.
For research use only. We do not sell to patients.
- Purity: 99.43%
- CAS No.: 108825-65-6
- Formula: C15H15N5O
- Molecular Weight:281.32
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 108825-65-6
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Appearance Solid
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Molecular Weight 281.32
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Formula C15H15N5O
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Color Off-white to light yellow
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SMILES
CN(C(C)=O)C1=CC=CC(C2=NN3C(C)=NN=C3C=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (177.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5547 mL | 17.7734 mL | 35.5468 mL | 88.8671 mL |
| 5 mM | 0.7109 mL | 3.5547 mL | 7.1094 mL | 17.7734 mL | |
| 10 mM | 0.3555 mL | 1.7773 mL | 3.5547 mL | 8.8867 mL | |
| 15 mM | 0.2370 mL | 1.1849 mL | 2.3698 mL | 5.9245 mL | |
| 20 mM | 0.1777 mL | 0.8887 mL | 1.7773 mL | 4.4434 mL | |
| 25 mM | 0.1422 mL | 0.7109 mL | 1.4219 mL | 3.5547 mL | |
| 30 mM | 0.1185 mL | 0.5924 mL | 1.1849 mL | 2.9622 mL | |
| 40 mM | 0.0889 mL | 0.4443 mL | 0.8887 mL | 2.2217 mL | |
| 50 mM | 0.0711 mL | 0.3555 mL | 0.7109 mL | 1.7773 mL | |
| 60 mM | 0.0592 mL | 0.2962 mL | 0.5924 mL | 1.4811 mL | |
| 80 mM | 0.0444 mL | 0.2222 mL | 0.4443 mL | 1.1108 mL | |
| 100 mM | 0.0355 mL | 0.1777 mL | 0.3555 mL | 0.8887 mL |
Lin28-let-7 antagonist 1 Related Classifications
HY-112659 Related Classifications
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