GAS7 - growth arrest specific 7 Gene

Homo sapiens

Gene ID: 8522 | Gene type: protein coding

About GAS7

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:9,910,606-10,198,606 (from NCBI)

This gene has 19 transcripts (splice variants), 273 orthologues, 5 paralogues and is associated with 74 phenotypes. Broad expression in brain (RPKM 53.9), skin (RPKM 13.3) and 17 other tissues.

Summary

Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008]

GAS7 Products(4)

mRNA	Protein	Name
NM_001130831.2	NP_001124303.1	growth arrest-specific protein 7 isoform d
NM_003644.3	NP_003635.2	growth arrest-specific protein 7 isoform a
NM_201432.2	NP_958836.1	growth arrest-specific protein 7 isoform b
NM_201433.2	NP_958839.1	growth arrest-specific protein 7 isoform c

GAS7 Protein Structure

SH3_9

FCH

0
100
200
300
400
476 a.a.

Protein Preferred Names

Protein Names

growth arrest-specific protein 7

Recombinant GAS7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70208	GAS7 Protein, Human (His)	O60861-1 (M1-I412)	≥95%

Related Diseases

Diseases

Alias

Glaucoma, Primary Open Angle

Glaucoma 1, Open Angle, E	Primary Open Angle Glaucoma
POAG	Adult-Onset Primary Open Angle Glaucoma
Chronic Simple Glaucoma	GLC1E
Primary Open Angle Glaucoma 1e	Glaucoma, Open Angle, Primary

Glaucoma, Normal Tension

Low Tension Glaucoma	Glaucoma, Normal Tension, Susceptibility To
Normal Tension Glaucoma	Ntg
Glaucoma, Normal Pressure	NPG
Glaucoma, Normal Pressure, Susceptibility To	Poag/Npg - [Normal Pressure Primary Open-Angle Glaucoma]

Primary Angle-Closure Glaucoma

Primary Angle Closure Glaucoma	Angle Closure Glaucoma
Acg - [Angle Closure Glaucoma]	Angle-Closure Glaucoma
Closed Angle Glaucoma	Acute Glaucoma
Prodromal Angle Closure Glaucoma

Open-Angle Glaucoma

Glaucoma Simplex	Pigmentary Glaucoma
Wide-Angle Glaucoma	Glaucoma, Open-Angle
Open Angle Glaucoma	Glaucoma Open-Angle
Chronic Simple Glaucoma	Coag - [Chronic Open-Angle Glaucoma]
Csg - [Chronic Simple Glaucoma]	Poag - [Primary Open-Angle Glaucoma]
Oag - [Open-Angle Glaucoma]	Chronic Glaucoma
Chronic Open Angle Glaucoma	Simple Glaucoma
Chronic Noncongestive Glaucoma	Ltg - [Low Tension Glaucoma]
Noncongestive Glaucoma	Nonobstructive Glaucoma
Normal Pressure Glaucoma	Primary Low Tension Glaucoma
Low-Tension Glaucoma	Residual Stage Low Tension Glaucoma
Open Cleft Glaucoma

Phacogenic Glaucoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05286	GAS7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GAS7	VGNC	VGNC:72886
Mus musculus	GAS7	MGD	MGI:1202388
Felis catus	GAS7	VGNC	VGNC:62470
Bos taurus	GAS7	VGNC	VGNC:29262
Canis familiaris	GAS7	VGNC	VGNC:41119
Rattus norvegicus	GAS7	RGD	RGD:621550
Others	GAS7	NCBI