Slc9b2 - solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 Gene

Also Known as NHA2; NHE10; nhaoc; Nhedc2; nha-oc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 97086

Summary

Predicted to enable identical protein binding activity; lithium:proton antiporter activity; and sodium:proton antiporter activity. Involved in clathrin-dependent endocytosis; flagellated sperm motility; and regulation of Insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within positive regulation of osteoclast development. Located in basolateral plasma membrane; cytoplasmic vesicle membrane; and sperm principal piece. Is expressed in alimentary system; brain; femur; male reproductive gland or organ; and mesenteric adipose tissue. Orthologous to human SLC9B2 (solute carrier family 9 member B2). [provided by Alliance of Genome Resources, Apr 2022]

Slc9b2 Products (3)

mRNA Protein Name
NM_001411266.1 NP_001398195.1 sodium/hydrogen exchanger 9B2 isoform 2
NM_001411267.1 NP_001398196.1 sodium/hydrogen exchanger 9B2 isoform 3
NM_178877.7 NP_849208.4 sodium/hydrogen exchanger 9B2 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in clathrin-dependent endocytosis IDA
IDA: Inferred from direct assay
23720317 MGI
involved in flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
27010853 MGI
acts upstream of or within positive regulation of osteoclast development IDA
IDA: Inferred from direct assay
18269914 MGI
involved in regulation of insulin secretion involved in cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
23720317 MGI
involved in sodium ion homeostasis IDA
IDA: Inferred from direct assay
27909897 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
27909897 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
20441802 MGI
located in endosome membrane IDA
IDA: Inferred from direct assay
23720317 MGI
NOT located in mitochondrial membrane IDA
IDA: Inferred from direct assay
23720317 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
20441802 MGI
located in recycling endosome IDA
IDA: Inferred from direct assay
32956652 MGI
located in sperm principal piece IMP
IMP: Inferred from mutant phenotype
27010853 MGI
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
23720317 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/hydrogen exchanger 9B2

  • NHE domain-containing protein 2

  • Na(+)/H(+) exchanger NHA2

  • Na(+)/H(+) exchanger-like domain-containing protein 2

  • Na+/H+ exchanger domain containing 2

  • mitochondrial Na(+)/H(+) exchanger NHA2

  • mitochondrial sodium/hydrogen exchanger 9B2

  • mitochondrial so

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13350 SLC9B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc9b2 NCBI NCBI:133308