Cep152 - centrosomal protein 152 Gene

Mus musculus

Also known as mKIAA0912

Gene ID: 99100 | Gene type: protein coding

About Cep152

Summary

Predicted to enable protein kinase binding activity. Involved in centriole replication and de novo centriole assembly involved in multi-ciliated epithelial cell differentiation. Located in centrosome and deuterosome. Is expressed in brain; pharynx epithelium; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in Seckel syndrome 5 and primary autosomal recessive microcephaly 9. Orthologous to human CEP152 (centrosomal protein 152). [provided by Alliance of Genome Resources, Apr 2022]

Cep152 Products(1)

mRNA	Protein	Name
NM_001081091.1	NP_001074560.1	centrosomal protein of 152 kDa

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20360068	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in centriole replication	IMP IMP: Inferred from mutant phenotype	24240477	MGI
involved in de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	IMP IMP: Inferred from mutant phenotype	24240477	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in centrosome	IDA IDA: Inferred from direct assay	26158450	MGI
located in deuterosome	IDA IDA: Inferred from direct assay	24240477	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

centrosomal protein of 152 kDa

Cep152 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Cep152	A2AUM9	Deup1	Mus musculus	Q7M6Y5	Anti Bait CoIP	24240477
Intra	Cep152	A2AUM9	Cep63	Mus musculus	Q3UPP8	Anti Bait CoIP	24240477
Cross	Cep152	A2AUM9	CEP63	Homo sapiens	Q96MT8	Anti Tag CoIP	24240477
Cross	Cep152	A2AUM9	CEP63	Homo sapiens	Q96MT8	Anti Tag CoIP	26496610
Cross	Cep152	A2AUM9	CEP63	Homo sapiens	Q96MT8	TAP	20360068

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02502	CEP152 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cep152	NCBI	NCBI:22995

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