Cep152 - centrosomal protein 152 Gene

Also Known as mKIAA0912

Species: Mus musculus

Gene Type: protein coding
Gene ID: 99100

Summary

Predicted to enable protein kinase binding activity. Involved in centriole replication and de novo centriole assembly involved in multi-ciliated epithelial cell differentiation. Located in centrosome and deuterosome. Is expressed in brain; pharynx epithelium; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in Seckel syndrome 5 and primary autosomal recessive microcephaly 9. Orthologous to human CEP152 (centrosomal protein 152). [provided by Alliance of Genome Resources, Apr 2022]

Cep152 Products (1)

mRNA Protein Name
NM_001081091.1 NP_001074560.1 centrosomal protein of 152 kDa

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20360068 MGI
Biological Process GO Annotation Evidence References Source
involved in centriole replication IMP
IMP: Inferred from mutant phenotype
24240477 MGI
involved in de novo centriole assembly involved in multi-ciliated epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
24240477 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
26158450 MGI
located in deuterosome IDA
IDA: Inferred from direct assay
24240477 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

centrosomal protein of 152 kDa

Cep152 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cep152 A2AUM9 Deup1 Mus musculus Q7M6Y5
Anti Bait CoIP
24240477
Intra
Cep152 A2AUM9 Cep63 Mus musculus Q3UPP8
Anti Bait CoIP
24240477
Cross
Cep152 A2AUM9 CEP63 Homo sapiens Q96MT8
Anti Tag CoIP
24240477
Cross
Cep152 A2AUM9 CEP63 Homo sapiens Q96MT8
Anti Tag CoIP
26496610
Cross
Cep152 A2AUM9 CEP63 Homo sapiens Q96MT8
TAP
20360068
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02502 CEP152 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cep152 NCBI NCBI:22995