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I-CBP112 hydrochloride

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Based on 5 publication(s) in Google Scholar

I-CBP112 hydrochloride is a selective inhibitor of CBP/P300 that directly binds their bromodomains (Kds = 142 and 625 nM, respectively). I-CBP112 significantly reduces the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells in a dose-dependent manner in vitro and in vivo. I-CBP112 increases the cytotoxic activity of BET bromodomain inhibitor JQ1 as well as doxorubicin.

For research use only. We do not sell to patients.

  • CAS No.: 2147701-33-3
  • Formula: C27H37ClN2O5
  • Molecular Weight:505.05
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • I-CBP112 hydrochloride Chemical Structure
    I-CBP112 hydrochloride Chemical Structure
CAS No.: 2147701-33-3
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609-228-6898
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • I-CBP112 hydrochloride Chemical Structure
    I-CBP112 hydrochloride Chemical Structure
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  • I-CBP112 hydrochloride