CSN1S1 - casein alpha s1 Gene

Also Known as CASA; CSN1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1446

About CSN1S1

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:69,931,068-69,946,574 (from NCBI)

This gene has 6 transcripts (splice variants) and 54 orthologues. Restricted expression toward fat (RPKM 9.4).

Summary

Predicted to be involved in response to dehydroepiandrosterone; response to estradiol; and response to steroid hormone. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

CSN1S1 Products (2)

mRNA Protein Name
NM_001025104.2 NP_001020275.1 alpha-S1-casein isoform 2 precursor
NM_001890.2 NP_001881.1 alpha-S1-casein isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-S1-casein

  • casein, alpha

CSN1S1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CSN1S1 P47710 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
CSN1S1 P47710 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
CSN1S1 P47710 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

CSN1S1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P81141 Casein Antibody (YA3488) WB, IP Human

Related Diseases

Diseases Alias
Milk Allergy

  • Milk Allergic Reaction

  • Milk Hypersensitivity

  • Allergy Milk
Food Allergy

  • Food Hypersensitivity

  • Food Allergies

  • Allergy Food

  • Food Allergen-Induced Hypersensitivity
Palmoplantar Keratoderma And Congenital Alopecia 2

  • Cataract-Alopecia-Sclerodactyly Syndrome

  • Cass

  • Autosomal Recessive Palmoplantar Keratoderma And Congenital Alopecia

  • PPKCA2

  • Autosomal Recessive Palmoplantar Hyperkeratosis And Congenital Alopecia

  • Palmoplantar Keratoderma And Congenital Alopecia, Wallis Type

  • Ppk-Ca, Wallis Type

  • Cataract, Alopecia, Sclerodactyly

  • Ppkca, Wallis Type

  • Ppkca Wallis Type

  • Cataract, Alopecia, Sclerodactyly Syndrome
Cow Milk Allergy

  • Bos Taurus Milk Allergy

  • Cow'S Milk Protein Sensitivity
Peanut Allergy

  • Allergy To Peanuts

  • Peanut Allergic Reaction

  • Allergies Peanut

  • Peanut Hypersensitivity
Lactose Intolerance

  • Lactose Malabsorption

  • Lm - Lactose Malabsorption

  • Alactasia

  • Dairy Product Intolerance

  • Hypolactasia

  • Milk Sugar Intolerance

  • Cow Milk Enteropathy

  • Intolerance Or Malabsorption Of Lactose

  • Lm - [Lactose Malabsorption]

  • Milk Intolerance
Goat Milk Allergy

  • Capra Hircus Milk Allergy
Interstitial Myocarditis
Perinatal Necrotizing Enterocolitis

  • Necrotizing Enterocolitis

  • Enterocolitis Necrotizing

  • Enterocolitis, Necrotizing

  • Necrotizing Enterocolitis In Fetus Or Newborn

  • Perinatal Necrotising Enterocolitis

  • Pseudomembranous Enterocolitis In Newborn

  • Nec
Mycetoma

  • Madura Foot

  • Mycetoma Of Foot
Dental Caries

  • Dental Caries Extending Into Pulp

  • Dental Caries Of Smooth Surface

  • Dental Caries Pit And Fissure

  • Smooth Surface Dental Caries

  • Dental Decay

  • Carious Teeth

  • Dental Cavity

  • Saprodontia

  • Teeth Decayed

  • Tooth Caries

  • Tooth Decay
Ige Responsiveness, Atopic

  • ATOPY

  • Atopy, Susceptibility To

  • Ige, Elevated Level Of

  • IGER

  • Immunoglobulin E, Basic Level Of, In Serum

  • Ige, Level Of

  • Igel

  • Ige Response Underlying Allergic Asthma And Rhinitis

  • Atopic Hypersensitivity

  • Immediate Hypersensitivity
Allergic Disease

  • Hypersensitivity

  • Allergic Hypersensitivity Disease

  • Allergic Condition

  • Allergic Reaction

  • Allergic Disposition
Arthritis

  • Inflammatory Joint Disease

  • Inflammatory Disorder Of Joint
Mastitis

  • Breast Inflammation

  • Inflammatory Breast Disease

  • Inflammatory Disease Of Breast

  • Inflammation Of Non-Human Mammary Gland

  • Inflammatory Disorder Of Breast

  • Mastitis Nos

  • Acute Mastitis Nos

  • Acute Nonpuerperal Mastitis

  • Nonpuerperal Mastitis Nos

  • Subacute Mastitis Nos
Dermatitis, Atopic

  • Atopic Dermatitis

  • Atopic Eczema

  • Dermatitis, Atopic, Susceptibility To, 1

  • Atod

  • Eczema, Atopic

  • Dermatitis, Atopic 1

  • Allergic Dermatitis

  • Atopic Neurodermatitis

  • Besnier'S Prurigo

  • Dermatitis, Atopic, 1

  • Dermatitis Atopic

  • Eczema

  • Besnier Prurigo
Autism

  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic
Dyslexia
Type 2 Diabetes Mellitus

  • Insulin Resistance

  • NIDDM

  • Type 2 Diabetes

  • Diabetes Mellitus, Non-Insulin-Dependent

  • T2D

  • Noninsulin-Dependent Diabetes Mellitus

  • Diabetes Mellitus, Type Ii

  • Maturity-Onset Diabetes

  • Insulin Resistance, Severe, Digenic

  • Diabetes Mellitus, Type 2

  • Diabetes Mellitus, Noninsulin-Dependent

  • Diabetes Mellitus, Noninsulin-Dependent, Association With

  • Diabetes Mellitus, Noninsulin-Dependent, Late Onset

  • Hypertension, Insulin Resistance-Related, Susceptibility To

  • Insulin Resistance, Susceptibility To

  • Non-Insulin-Dependent Diabetes Mellitus

  • Type Ii Diabetes Mellitus

  • Adult-Onset Diabetes Mellitus

  • Maturity-Onset Diabetes Mellitus

  • Diabetes Mellitus Type 2

  • Type Ii Diabetes

  • Type 2 Diabetes Mellitus, Susceptibility To

  • Diabetes, Type 2

  • Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

  • Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

  • Diabetes Mellitus, Type 2, Susceptibility To

  • Diabetes Mellitus, Noninsulin-Dependent, 2

  • Diabetes Mellitus, Type Ii, Susceptibility To

  • Hypertension, Insulin Resistance-Related

  • Adult-Onset Diabetes

  • Aodm

  • Diabetes Mellitus, Adult-Onset

  • Diabetes Mellitus Type Ii

  • Diabetes Mellitus Type 2, Susceptibility To

  • Diabetes, Type Ii, Susceptibility To

  • Diabetes Type 2

  • Diabetes Mellitus

  • Adult Onset Diabetes

  • Maturity Onset Diabetes

  • Nonketotic Diabetes

  • Non-Insulin Dependent Diabetes Mellitus

  • T2dm - [Type 2 Diabetes Mellitus]

  • Niddm - [Non Insulin Dependent Diabetes Mellitus]

  • Dm2

  • Dm Type Ii

  • Diabetic Type 2

  • Insulin Requiring Type 2 Diabetes

  • Noninsulin Dependent Diabetes

  • Non-Insulin-Dependent Diabetes Mellitus Without Complications

  • Diabetes Due To Insulin Secretory Defect

  • Diabetes Mellitus Due To Insulin Secretory Defect

  • Non-Insulin-Dependent Diabetes Of The Young

  • Senile Diabetes

  • Nonketotic Hyperglycaemia

  • Stable Diabetes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03242 CSN1S1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CSN1S1 VGNC VGNC:39664
Mus musculus CSN1S1 MGD MGI:88540
Bos taurus CSN1S1 VGNC VGNC:27763
Felis catus CSN1S1 VGNC VGNC:107322
Rattus norvegicus CSN1S1 RGD RGD:2430
Others CSN1S1 NCBI