CDK8 ligand 2
CDK8 ligand 2 is a steroidal CDK8 and CDK19 inhibitor with IC50 values of 16 nM and 8 nM, respectively. CDK8 ligand 2 shows no activity against NEK1 (IC50 >10,000 nM). As a target protein ligand, CDK8 ligand 2 is used for the synthesis of the CDK8 PROTAC degrader (HY-111518).
For research use only. We do not sell to patients.
- CAS No.: 2374703-22-5
- Formula: C30H42N2
- Molecular Weight:430.67
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
CDK8 16 nM (IC50) |
CDK19 8 nM (IC50) |
Chemical Information
-
CAS No. 2374703-22-5
-
Molecular Weight 430.67
-
Formula C30H42N2
-
SMILES
CN(C)[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H](C5=CC6=C(C=C5)C=CN=C6)CC[C@@]4([H])[C@]3([H])CC[C@@]2([H])C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK8 ligand 2 Related Classifications
HY-184544 Related Classifications
Powered by Bioz