bisSP1
Based on 1 Customer Validation
bisSP1 is an antibody-drug conjugate linker (ADC Linkers). bisSP1 is also a click chemistry reagent that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 2253947-15-6
- 分子式: C12H23N9O2
- 分子量:325.37
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
bisSP1 (2253947-15-6) acts as an ADC linker to conjugate with N297Q-mutated anti-FGFR2b antibodies (mAb1, mAb2) and drug linker 3, forming intact antibody-drug conjugates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2253947-15-6
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性状 Liquid
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分子量 325.37
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分子式 C12H23N9O2
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Color Colorless to light yellow
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SMILES
[N-]=[N+]=NCCC(N[C@@H](CCCCN)C(NCCCN=[N+]=[N-])=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (307.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0734 mL | 15.3671 mL | 30.7342 mL | 76.8356 mL |
| 5 mM | 0.6147 mL | 3.0734 mL | 6.1468 mL | 15.3671 mL | |
| 10 mM | 0.3073 mL | 1.5367 mL | 3.0734 mL | 7.6836 mL | |
| 15 mM | 0.2049 mL | 1.0245 mL | 2.0489 mL | 5.1224 mL | |
| 20 mM | 0.1537 mL | 0.7684 mL | 1.5367 mL | 3.8418 mL | |
| 25 mM | 0.1229 mL | 0.6147 mL | 1.2294 mL | 3.0734 mL | |
| 30 mM | 0.1024 mL | 0.5122 mL | 1.0245 mL | 2.5612 mL | |
| 40 mM | 0.0768 mL | 0.3842 mL | 0.7684 mL | 1.9209 mL | |
| 50 mM | 0.0615 mL | 0.3073 mL | 0.6147 mL | 1.5367 mL | |
| 60 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.2806 mL | |
| 80 mM | 0.0384 mL | 0.1921 mL | 0.3842 mL | 0.9604 mL | |
| 100 mM | 0.0307 mL | 0.1537 mL | 0.3073 mL | 0.7684 mL |
bisSP1 関連分類
HY-147325 関連分類
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