CDK7-IN-6
CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2378710-04-2
- 分子式: C26H34ClN9O
- 分子量:524.06
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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CDK7 ≤100 nM (IC50) |
CDK7-IN-6 inhibits the viability of HCT116, H460, MV4-11, A2780, and OVCAR cells (IC50≤1 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2378710-04-2
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分子量 524.06
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分子式 C26H34ClN9O
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SMILES
ClC1=CC=CC(N2N=C(C(C)(C)O)C=C2)=C1CNC3=NC(N4CCC(CC4)N)=NC5=C(C(C)C)C=NN35
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)