2378710-04-2
Chemical Structure
CDK7-IN-6
- CAS No.: 2378710-04-2
- Formula:C26H34ClN9O
- Molecular Weight:524.06
IUPAC Name: 2-(1-(2-(((2-(4-aminopiperidin-1-yl)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)-3-chlorophenyl)-1H-pyrazol-3-yl)propan-2-ol
InChIKey: FHJUWCCXYSHDGT-UHFFFAOYSA-N
SMILES: ClC1=CC=CC(N2N=C(C(C)(C)O)C=C2)=C1CNC3=NC(N4CCC(CC4)N)=NC5=C(C(C)C)C=NN35
Biological Activity: CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1].
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CDK7-IN-6 | CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer. | |||||||||||||||||||||
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Keywords
