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CDH19 - cadherin 19 Gene

Also Known as CDH7; CDH7L2

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 28513

About CDH19

Cytogenetic location: 18q22.1 Genomic coordinates (GRCh38): 18:66,501,083-66,604,090 (from NCBI)

This gene has 5 transcripts (splice variants), 125 orthologues and 33 paralogues. Broad expression in heart (RPKM 5.1), adrenal (RPKM 2.5) and 19 other tissues.

Summary

This gene is one of three related type II Cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular Cadherin repeats. Loss of Cadherins may be associated with Cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012]

CDH19 Products (2)

mRNA	Protein	Name
NM_001271028.2	NP_001257957.1	cadherin-19 isoform 2 preproprotein
NM_021153.4	NP_066976.1	cadherin-19 isoform 1 preproprotein

CDH19 Protein Structure

Cadherin

Cadherin_C

0
200
400
600
772 a.a.

Protein Preferred Names	Protein Names
cadherin-19	cadherin 19, type 2

Recombinant CDH19 Proteins

製品番号	製品名	アクセッション番号	純度
HY-P700973	CDH19 Protein, Human (Flag-MBP)	Q9H159-1 (G44-H569)	≥ 95%, as determined by reducing SDS-PAGE.

CDH19 抗体

製品番号	製品名	アプリケーション	反応性
HY-P811055	Cadherin 19 Antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat, Monkey

関連疾患

Diseases	Alias
Achilles Bursitis	Achilles Bursitis Or Tendinitis Capped Hock Haglund'S Deformity Haglund'S Disease Osteochondritis Of The Talus
Craniofacial-Deafness-Hand Syndrome	CDHS Craniofacial Deafness Hand Syndrome Sommer-Young-Wee-Frye Syndrome Features Of Flat Facial Profile, Hypertelorism, Hypoplastic Nose With Slitlike Nares, And A Sensorineural Hearing Loss Craniofacial-Hearing Loss-Hand Syndrome
Choanal Atresia, Posterior	Choanal Atresia Atresia Of Nares Posterior Choanal Atresia PCA Imperforate Nares Choanal Fusion Congenital Stenosis Of Nares Congenital Stenosis Of Choanae Nasal Atresia Nos
Charge Syndrome	Charge Association Hall-Hittner Syndrome Charge Association--Coloboma, Heart Anomaly, Choanal Atresia, Retardation, Genital And Ear Anomalies Hhs Coloboma, Heart Anomaly, Choanal Atresia, Restriction Of Growth And Development, Genital And Ear Anomalies Coloboma-Heart Defects-Atresia Choanae-Retardation Of Growth And Development-Genitourinary Problems-Ear Abnormalities Syndrome CHARGES
Coloboma Of Macula	Coloboma Congenital Ocular Coloboma Microphthalmia, Isolated, With Coloboma Agenesis Of Macula Hereditary Macular Coloboma Ocular Coloboma Coloboma Of Eye Macular Coloboma Uveoretinal Coloboma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS02329	CDH19 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS03575	DCHS1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21512	Cdh19 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28030	Cdh19 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

阻害性抗体 (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-P992217	Anti-CDH19 Antibody		/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Felis catus	CDH19	VGNC	VGNC:60677
Rattus norvegicus	CDH19	RGD	RGD:1307169
Mus musculus	CDH19	MGD	MGI:3588198
Canis familiaris	CDH19	VGNC	VGNC:39027
Macaca mulatta	CDH19	VGNC	VGNC:70812
Others	CDH19	NCBI