Wee1 - WEE1 G2 checkpoint kinase Gene
生物種: Rattus norvegicus
遺伝子タイプ: protein coding
遺伝子ID: 308937
About Wee1
Primary_assembly 1: 164,174,779-164,197,688 forward strand.mRatBN7.2:CM026974.1
This gene has 2 transcripts (splice variants), 227 orthologues, 8 paralogues and is associated with 1 phenotype. Biased expression in Testes (RPKM 65.2), Thymus (RPKM 58.) and 9 other tissues.
Summary
Predicted to enable protein tyrosine kinase activity. Predicted to be involved in cell division and mitotic cell cycle. Predicted to act upstream of or within several processes, including establishment of cell polarity; neuron projection morphogenesis; and peptidyl-tyrosine phosphorylation. Predicted to be located in cytoplasm and nucleolus. Predicted to be active in nucleus. Orthologous to human Wee1 (Wee1 G2 checkpoint kinase). [provided by Alliance of Genome Resources, Apr 2022]
Wee1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001012742.1 | NP_001012760.1 | wee1-like protein kinase |
Wee1 Protein Structure
PTKc_Wee1a
PTKc_Wee1a: cd14138 (291 - 566)
- 0
- 100
- 200
- 300
- 400
- 500
- 600
- 646 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
wee1-like protein kinase |
|
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(3)
| 製品番号 | 製品名 |
製品効果
|
純度 |
Phase
|
|---|---|---|---|---|
| HY-10993 | Adavosertib | Inhibitor | 99.96% | Phase 2 |
| HY-145817A | lunresertib | Inhibitor | 99.97% | Phase 2 |
| HY-182906 | XL495 | Inhibitor | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(70)
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-132295 | Azenosertib | Inhibitor | 99.96% | Unkown |
| HY-13925 | PD0166285 | Inhibitor | 99.46% | Unkown |
| HY-147054 | Zedoresertib | Inhibitor | 99.85% | Unkown |
| HY-175749 | BMS-986463 | Degrader | 98.63% | Unkown |
| HY-N0819 | Raddeanin A | Inhibitor | 98.68% | Unkown |
| HY-122113 | PD173952 | Inhibitor | 99.58% | Unkown |
| HY-18961 | PD 407824 | Inhibitor | 99.00% | Unkown |
| HY-W1135319 | SB-405483 | 99.33% | Unkown | |
| HY-133618 | Pomalidomide-C3-adavosertib | Degrader | 99.84% | Unkown |
| HY-148065 | FMF-06-098-1 | Inhibitor | 98.77% | Unkown |
| HY-147312 | GSK-1520489A | Inhibitor | 99.83% | Unkown |
| HY-108343 | WEE1-IN-4 | Inhibitor | 99.70% | Unkown |
| HY-103029 | Bosutinib isomer | Inhibitor | 99.62% | Unkown |
| HY-148062 | RSS0680 | 98.03% | Unkown | |
| HY-145817 | (Rac)-lunresertib | Inhibitor | 99.72% | Unkown |
| HY-170517 | PKMYT1-IN-8 | Inhibitor | 99.31% | Unkown |
| HY-173320 | HEMTAC WEE1 degrader-1 | Degrader | 99.78% | Unkown |
| HY-144999 | LEB-03-146 | 98.08% | Unkown | |
| HY-138239 | WEE1-IN-3 | Inhibitor | 98.64% | Unkown |
| HY-145664 | Myt1-IN-1 | Inhibitor | 98.97% | Unkown |
| HY-161880 | WEE1-IN-10 | Inhibitor | / | Unkown |
| HY-168654 | WEE1 degrader 1 | Degrader | 99.74% | Unkown |
| HY-163697 | WEE1-IN-7 | Inhibitor | 99.70% | Unkown |
| HY-145666 | Myt1-IN-3 | Inhibitor | 99.14% | Unkown |
| HY-W070306 | PDK1-IN-1 | Inhibitor | 99.95% | Unkown |
| HY-169946 | WEE1/PKMYT1-IN-1 | Inhibitor | 98.84% | Unkown |
| HY-163490 | PKMYT1-IN-1 | Inhibitor | 99.24% | Unkown |
| HY-145817B | (R)-lunresertib | Inhibitor | 99.87% | Unkown |
| HY-180485 | PROTAC D16-M1P2 | Degrader | / | Unkown |
| HY-145665 | Myt1-IN-2 | Inhibitor | / | Unkown |
| HY-163491 | PKMYT1-IN-2 | Inhibitor | / | Unkown |
| HY-169946B | WEE1/PKMYT1-IN-3 | Inhibitor | / | Unkown |
| HY-178190 | WEE1-IN-13 | Inhibitor | / | Unkown |
| HY-178150 | WEE1-IN-14 | Inhibitor | / | Unkown |
| HY-133703A | i-AZD1775 TFA | Inhibitor | / | Unkown |
| HY-13925A | PD0166285 dihydrochloride | Inhibitor | / | Unkown |
| HY-182791 | BAA-009 | Inhibitor | / | Unkown |
| HY-183278 | APO-50815 | Inhibitor | / | Unkown |
| HY-176957 | PKMYT1-IN-11 | Inhibitor | / | Unkown |
| HY-143342 | LEB-03-144 | / | Unkown | |
| HY-175817 | PKMYT1-IN-10 | Inhibitor | / | Unkown |
| HY-157443 | Myt1-IN-4 | Inhibitor | / | Unkown |
| HY-183547 | WEE1/PKMYT1-IN-4 | Inhibitor | / | Unkown |
| HY-176283 | Tubulin/LSD1-IN-1 | Inhibitor | / | Unkown |
| HY-160948 | DB07006 | Inhibitor | / | Unkown |
| HY-179272 | Wee1/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-160530 | WEE1-IN-6 | Inhibitor | / | Unkown |
| HY-143340 | LEB-03-145 | / | Unkown | |
| HY-172759 | PKMYT1-IN-9 | Inhibitor | / | Unkown |
| HY-180484 | PKMYT1-IN-12 | Inhibitor | / | Unkown |
| HY-174448 | WEE1-IN-12 | Inhibitor | / | Unkown |
| HY-143343 | LEB-03-153 | / | Unkown | |
| HY-172807 | p38α-IN-9 | Inhibitor | / | Unkown |
| HY-162849 | PKMYT1-IN-3 | Inhibitor | / | Unkown |
| HY-176363 | Adavosertib-C3-NH-Boc | Inhibitor | / | Unkown |
| HY-168180 | WEE1-IN-11 | Inhibitor | / | Unkown |
| HY-180893 | XH-30 | Inhibitor | / | Unkown |
| HY-169946A | WEE1/PKMYT1-IN-2 | Inhibitor | / | Unkown |
| HY-175261 | DHI1 | Inhibitor | / | Unkown |
| HY-182790 | BAA-065 | Inhibitor | / | Unkown |
| HY-175819 | PD-166285 | Inhibitor | / | Unkown |
| HY-161871 | WEE1-IN-8 | Inhibitor | / | Unkown |
| HY-182433 | CJM061 | Inhibitor | / | Unkown |
| HY-161879 | WEE1-IN-9 | Inhibitor | / | Unkown |
| HY-162986 | PKMYT1-IN-4 | Inhibitor | / | Unkown |
| HY-159937 | PKMYT1-IN-7 | Inhibitor | / | Unkown |
| HY-162988 | Myt1-IN-5 | Inhibitor | / | Unkown |
| HY-N0819R | Raddeanin A (Standard) | / | Unkown | |
| HY-162987 | PKMYT1-IN-6 | Inhibitor | / | Unkown |
| HY-176853 | Myt1-IN-6 | Inhibitor | / | Unkown |
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