Myt1-IN-4
Myt1-IN-4 (21) is an orally active and selective membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor, with an IC50 of 2.6 nM. Myt1-IN-4 (21) possesses antitumor activity.
For research use only. We do not sell to patients.
- Formula: C25H27N7O2
- Molecular Weight:457.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PKMYT1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCC1569 | IC50 |
0.21 μM
Compound: 21
|
Antiproliferative activity against human HCC1569 cells assessed as inhibition of cell growth incubated for 7 days by CTG assay
Antiproliferative activity against human HCC1569 cells assessed as inhibition of cell growth incubated for 7 days by CTG assay
|
[PMID: 38146659] |
Chemical Information
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Molecular Weight 457.53
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Formula C25H27N7O2
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SMILES
NC([N@@]1[C@@]2=C(C=CC(O)=C2C)C)=C(C3=NC(C4CC4)=C(N=C31)C)C(N5CCN6N=CC=C6C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)