DB07006
DB07006 (compound 18) is a potent, ATP-cpmpetitive dual inhibitor of Wee1 (IC50 = 0.030 μM) and Chk1 checkpoint kinases (IC50 = 0.018 μM). DB07006 demonstrates effective abrogation of the G2/M checkpoint in combination with DNA-damaging agents in cellular models. DB07006 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 622855-60-1
- Formula: C24H20N2O5
- Molecular Weight:416.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Chk1 0.018 μM (IC50) |
Wee1 0.030 μM (IC50) |
Chemical Information
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CAS No. 622855-60-1
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Molecular Weight 416.43
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Formula C24H20N2O5
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SMILES
O=C1NC(C2=C(C3=C(N4CCCO)C=CC(O)=C3)C4=CC(C5=C(OC)C=CC=C5)=C21)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DB07006 Related Classifications
HY-160948 Related Classifications
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