1. Cell Cycle/DNA Damage
  2. Wee1
  3. WEE1-IN-6

WEE1-IN-6 (compound 110) is a orally active WEE1 inhibitor with an DC50 value of ≦ 100 nM. WEE1-IN-6 inhibits cell proliferation.

For research use only. We do not sell to patients.

WEE1-IN-6 Chemical Structure

WEE1-IN-6 Chemical Structure

CAS No. : 2928524-08-5

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Description

WEE1-IN-6 (compound 110) is a orally active WEE1 inhibitor with an DC50 value of ≦ 100 nM. WEE1-IN-6 inhibits cell proliferation[1].

IC50 & Target

DC50: ≦ 100 nM (WEE1)[1]

In Vitro

WEE1-IN-6 (compound 110) shows anti-proliferation activity with an IC50 value of ≦ 25 nM in H1048 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

829.96

Formula

C45H52FN11O4

CAS No.
SMILES

FC1=C(C=CC(NC2C(NC(CC2)=O)=O)=C1)N(CC3)CCC3CN(CC4)CCN4C(C=C5)=CC=C5NC6=NC7=C(C(N(CC=C)N7C8=NC([C@@](O)(CC)CC9)=C9C=C8)=O)C=N6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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WEE1-IN-6 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
WEE1-IN-6
Cat. No.:
HY-160530
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