BAA-009
BAA-009 is a selective and orally active PKMYT1 inhibitor with an IC50 of <50 nM. BAA-009 inhibits cancer cells proliferation and inhibits tumor growth in OVCAR3 xenograft mice. BAA-009 can be used for the research of cancer, such as ovarian cancer.
For research use only. We do not sell to patients.
- Formula: C28H35N5O4S
- Molecular Weight:537.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PKMYT1 <50 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:human ovarian cancer OVCAR3 xenograft mice models[1]
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Dosage:40, 120 mg/kg
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Administration:p.o.; qd for 17 days
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Result:Inhibited tumor growth.
Showed stronger antitumor activity combined with Irinotecan (HY-16562) and ADC Mirvetuximab exatecan.
Chemical Information
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Molecular Weight 537.67
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Formula C28H35N5O4S
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SMILES
CC(C)(C)C(OC1=CC=C(C)C(NC(C2=CN=C(NC3=NC(NC(C(C)(C)C)=O)=CC=C3C)S2)=O)=C1C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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