PKMYT1-IN-12
PKMYT1-IN-12 (Compound 4) is a selective inhibitor of PKMYT1, with an IC₅₀ of 2.6 nM. PKMYT1-IN-12 can effectively inhibit the phosphorylation of CDK1, with an IC₅₀ of 44 nM. PKMYT1-IN-12 is a target protein ligand that can be used for the synthesis of PROTAC D16-M1P2 (HY-180485).
For research use only. We do not sell to patients.
- CAS No.: 2974454-59-4
- Formula: C20H16N6O
- Molecular Weight:356.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
PKMYT1 2.6 nM (IC50) |
CDK1 |
Chemical Information
-
CAS No. 2974454-59-4
-
Molecular Weight 356.38
-
Formula C20H16N6O
-
SMILES
N#CC1=C2C=C(C3=CN=C(N)N=C3)NC2=NC=C1C4=C(C)C(O)=CC=C4C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)