2974454-59-4
2974454-59-4
Chemical Structure
PKMYT1-IN-12
- CAS No.: 2974454-59-4
- Formula:C20H16N6O
- Molecular Weight:356.38
InChIKey: QJOLSGMHLAGFBN-UHFFFAOYSA-N
SMILES: N#CC1=C2C=C(C3=CN=C(N)N=C3)NC2=NC=C1C4=C(C)C(O)=CC=C4C
Biological Activity: PKMYT1-IN-12 (Compound 4) is a selective inhibitor of PKMYT1, with an IC₅₀ of 2.6 nM. PKMYT1-IN-12 can effectively inhibit the phosphorylation of CDK1, with an IC₅₀ of 44 nM. PKMYT1-IN-12 is a target protein ligand that can be used for the synthesis of PROTAC D16-M1P2 (HY-180485)[1].
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PKMYT1-IN-12 | PKMYT1-IN-12 (Compound 4) is a selective inhibitor of PKMYT1, with an IC₅₀ of 2.6 nM. PKMYT1-IN-12 can effectively inhibit the phosphorylation of CDK1, with an IC₅₀ of 44 nM. PKMYT1-IN-12 is a target protein ligand that can be used for the synthesis of PROTAC D16-M1P2 (HY-180485). | |||||||||||||||||||||
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References
Keywords
