PROTAC D16-M1P2
PROTAC D16-M1P2 is an orally active PKMYT1 PROTAC degrader with a DC50 of 0.7 nM. PROTAC D16-M1P2 also inhibits the activity of PKMYT1 with an IC50 of 7.6 nM. PROTAC D16-M1P2 inhibits pCDK1 with an IC50 of 9 nM. PROTAC D16-M1P2 has demonstrated significant anti-tumor efficacy in mouse models and can be used for research on breast cancer.
For research use only. We do not sell to patients.
- Formula: C43H45FN10O4
- Molecular Weight:784.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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PKMYT1 0.7 nM (DC50) |
PKMYT1 7.6 nM (IC50) |
CDK1 |
Cereblon |
Chemical Information
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Molecular Weight 784.88
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Formula C43H45FN10O4
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SMILES
N#CC1=[C@]([C@](C(C)=C(C=C2)O)=C2C)C=NC3=C1C=C(N3)C4=CN=C(N5CCC6(CC(N7CCN(C8=C(F)C=C(NC9CCC(NC9=O)=O)C=C8)CC7)CO6)CC5)N=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC D16-M1P2 Related Classifications
HY-180485 Related Classifications
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