PKMYT1-IN-11
PKMYT1-IN-11 (Example 1) is a PKMYT1 inhibitor with an IC50 of 4.49 nM. PKMYT1-IN-11 inhibits the proliferation of HCC1569 cells. When combined with Gemcitabine (HY-17026), PKMYT1-IN-11 shows a significant anti-tumor effect in the OVCAR3 xenograft mouse model. PKMYT1-IN-11 can be used for the study of various cancers such as breast cancer and ovarian cancer.
For research use only. We do not sell to patients.
- CAS No.: 3097325-25-9
- Formula: C18H16F4N4O2
- Molecular Weight:396.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3097325-25-9
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Molecular Weight 396.34
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Formula C18H16F4N4O2
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SMILES
NC1=C(C(N)=O)C2=C([N@@]1[C@@]3=C(C)C(O)=C(F)C=C3C)N=C(C)C(C(F)(F)F)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)