Myt1-IN-2
Myt1-IN-2 is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. Myt1-IN-2 has anticancer effects (WO2021195782A1; compound 28).
For research use only. We do not sell to patients.
- CAS No.: 2719748-43-1
- Formula: C18H16N6O2S
- Molecular Weight:380.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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PKMYT1 |
Chemical Information
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CAS No. 2719748-43-1
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Molecular Weight 380.42
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Formula C18H16N6O2S
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SMILES
O=C(C1=C(N)N(C2=C(C)C(O)=CC=C2C)C3=C1N=C(C4=NC=CS4)C=N3)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)