Arhgef1 - Rho guanine nucleotide exchange factor 1 Gene

Also Known as Lsc; Lbcl2

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 60323

Summary

Predicted to enable G protein-coupled receptor binding activity and guanyl-nucleotide exchange factor activity. Involved in negative regulation of cell death. Predicted to be located in cytosol and plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 62. Orthologous to human ARHGEF1 (Rho Guanine Nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef1 Products (1)

mRNA Protein Name
NM_021694.3 NP_067726.3 rho guanine nucleotide exchange factor 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence 参考文献 由来
involved in microtubule depolymerization IMP
IMP: Inferred from mutant phenotype
20858895 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 1

  • Lymphoid blast crisis-like 2

  • Rho guanine nucleotide exchange factor (GEF) 1

  • lbc's second cousin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS00945 ARHGEF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Arhgef1 NCBI NCBI:9138