NSD-IN-5
NSD-IN-5 is a nuclear receptor-binding SET domain (NSD) inhibitor with IC50 values of 6 nM and < 1 nM against NSD1 and NSD2, respectively. NSD-IN-5 can be used in research related to multiple myeloma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3034213-62-9
- 分子式: C26H28F2N8O2
- 分子量:522.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
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NSD2 < 1 nM (IC50) |
NSD1 6 nM (IC50) |
NSD-IN-5 potently inhibits NSD1 histone lysine methyltransferase activity in a cell-free assay with an average IC50 of 6 nM[1].
NSD-IN-5 potently inhibits NSD2 histone lysine methyltransferase activity in a cell-free assay with an average IC50 of <1 nM[1].
NSD-IN-5 inhibits H3K36 dimethylation in KMS11 cells with an average IC50 of 6 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3034213-62-9
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分子量 522.55
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分子式 C26H28F2N8O2
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SMILES
FC(C=C(C(F)=C1)OC)=C1C2=NC=C(N3C[C@](N)(CCC3)C(NC)=O)C(CC4=CN=C5N4C=CN=C5N)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NSD-IN-5 関連分類
HY-177400 関連分類
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