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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
PON1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "PON1" in MCE Product Catalog:
製品番号: HY-B0815S
CAS 番号: 285138-81-0
製品番号: HY-W015892
CAS 番号: 695-06-7
別名: γ-Caprolactone
製品番号: HY-W017445
CAS 番号: 2688-48-4
Category:
Target:
製品番号: HY-RS17965
Target:
研究分野:
Pon1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pon1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-143239
純度: 99.69%
Target:
研究分野:
PPARα/γ agonist 1 (compound 5b) is a potent and dual PPARα/γ partial agonist with EC50 values of 28 nM and 69 nM for PPARα and PPARγ, respectively. PPARα/γ agonist 1 is a promising prototype for dyslipidemia and diabetes research [1].
製品番号: HY-146058
CAS 番号: 2419107-97-2
Target:
研究分野:
NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities [1].
製品番号: HY-RS10872
Target:
研究分野:
PON1 Human Pre-designed siRNA Set A contains three designed siRNAs for PON1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS24436
Target:
研究分野:
Pon1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pon1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-W509797
CAS 番号: 21618-92-8
5-(3',4'-Dihydroxyphenyl)-γ-valerolactone is an intestinal microbiota metabolite of (-)-Epicatechin (HY-N0001). 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone downregulates TNF-α-stimulated phosphorylation of IKK and IκBα, inhibits the transcriptional activation of NF-κB, and suppresses the expression of adhesion molecules and chemokines. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone promotes autophagy, alleviates oxidative stress, maintains osteoblast differentiation, induces G1 phase arrest, inhibits adipogenesis, and scavenges ABTS free radicals. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone inhibits the adhesion of uropathogenic Escherichia coli to bladder epithelial cells; when used in combination with Curcumin (HY-N0005), it downregulates the NLRP3 and NOX2/Nrf2 signaling pathways, thereby reducing microglial activation. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone can be used in research related to diabetes, atherosclerosis, osteoporosis, obesity, neurodegenerative diseases involving microglial activation, and urinary tract infections [1] .
製品番号: HY-130220
CAS 番号: 81517-87-5
Target:
研究分野:
(±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation [1] .
製品番号: HY-W015892R
CAS 番号: 695-06-7
別名: γ-Caprolactone (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
