695-06-7
695-06-7
Chemical Structure
γ-Hexalactone
Synonym(s): γ-Caprolactone
- CAS No.: 695-06-7
- Formula:C6H10O2
- Molecular Weight:114.14
IUPAC Name: 5-ethyldihydrofuran-2(3H)-one
InChIKey: JBFHTYHTHYHCDJ-UHFFFAOYSA-N
SMILES: O=C1OC(CC)CC1
Biological Activity: γ-Hexalactone (γ-Caprolactone) is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage in human lymphocytes and HepG2 cells, modulates cytokine secretion in human lymphocytes, and reduces recombinant PON1 activity. γ-Hexalactone serves as a dose-dependent oviposition inhibitor against Bactrocera oleae. γ-Hexalactone can be used for the research of Bactrocera oleae pest management[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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γ-Hexalactone | 99.46% | γ-Hexalactone (γ-Caprolactone) is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage in human lymphocytes and HepG2 cells, modulates cytokine secretion in human lymphocytes, and reduces recombinant PON1 activity. γ-Hexalactone serves as a dose-dependent oviposition inhibitor against Bactrocera oleae. γ-Hexalactone can be used for the research of Bactrocera oleae pest management. | ||||||||||||||||||||
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γ-Hexalactone (Standard) | ≥98% | γ-Hexalactone (Standard) is the analytical standard of γ-Hexalactone (γ-Caprolactone) (HY-W015892). This product is intended for research and analytical applications. γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage in human lymphocytes and HepG2 cells, modulates cytokine secretion in human lymphocytes, and reduces recombinant PON1 activity. γ-Hexalactone serves as a dose-dependent oviposition inhibitor against Bactrocera oleae. γ-Hexalactone can be used for the research of Bactrocera oleae pest management. | ||||||||||||||||||||
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References
- [1]. Shangula S, et al. PON1 increases cellular DNA damage by lactone substrates. Arch Toxicol. 2019;93(7):2035-2043. [Content Brief]
- [2]. Zuravski L, et al. Gamma-hexalactone flavoring causes DNA lesion and modulates cytokines secretion at non-cytotoxic concentrations. BMC Pharmacol Toxicol. 2019;20(Suppl 1):79. Published 2019 Dec 19. [Content Brief]
- [3]. López S, et al. A Pre-Exposure to Male-Specific Compound γ-Hexalactone Reduces Oviposition in Bactrocera oleae (Rossi) (Diptera: Tephritidae) Under Laboratory Conditions. Insects. 2025; 16(2):147.
- [4]. Api AM, et al. Update to RIFM fragrance ingredient safety assessment, γ-hexalactone, CAS Registry Number 695-06-7. Food Chem Toxicol. 2026;210 Suppl 1:115886. [Content Brief]
- [5]. Xin R, et al. E-Nose and GC-MS Reveal a Difference in the Volatile Profiles of White- and Red-Fleshed Peach Fruit. Sensors (Basel). 2018;18(3):765. Published 2018 Mar 2. [Content Brief]
