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United States

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製品番号: HY-183232

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SRS6-11

SRS6-11 is an iron death-independent necrotic cell death (Necrosis) inducer. SRS6-11 retains significant lethality in the presence of α-tocopherol (HY-W020044). SRS6-11 can be used in fibrosarcoma research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₂₃H₂₅F₂N₃O₅S₂
分子量:525.59

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

SRS6-11 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

SRS6-11 (0.001-100 μM; 48 h) induces ferroptosis-independent necrotic cell death in HT-1080 fibrosarcoma cells, with minimal rescue by the ferroptosis inhibitor α-tocopherol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

HT-1080 fibrosarcoma cells
Concentration:

0.001-100 μM
Incubation Time:

48 h
Result:

Induced cell death that retained substantial lethality in the presence of 100 μM α-tocopherol.
Decreased cell viability with increasing concentrations, and this decrease was only minimally suppressed by α-tocopherol across the tested concentration range.

化学情報

分子量 525.59
分子式 C₂₃H₂₅F₂N₃O₅S₂
SMILES

O=S(C1=CC=C2C(/C(C3=C2C=CC(S(=O)(N4CCCC(C4)F)=O)=C3)=N\O)=C1)(N5CCCC(C5)F)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Shimada K, et al. Dissecting Polypharmacology in Phenotypic Screening to Resolve Ferroptotic and Necrotic Cell-Death Mechanisms. ACS Med Chem Lett. 2026;17(4):876-883. Published 2026 Mar 24. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

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体積 _(開始) 体積 _(開始)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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